Liquiritin apioside attenuates laryngeal chemoreflex but not mechanoreflex in rat pups
نویسندگان
چکیده
منابع مشابه
Elevated body temperature enhances the laryngeal chemoreflex in decerebrate piglets.
Hyperthermia and reflex apnea may both contribute to sudden infant death syndrome (SIDS). Therefore, we investigated the effect of increased body temperature on the inhibition of breathing produced by water injected into the larynx, which elicits the laryngeal chemoreflex (LCR). We studied decerebrated, vagotomized, neonatal piglets aged 3-15 days. Blood pressure, end-tidal CO(2), body temperat...
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Isolated rat pups respond to cold exposure physiologically by increasing metabolic heat production and behaviorally by emitting ultrasound. The relationship between these 2 responses was investigated by monitoring oxygen consumption, heat production by brown adipose tissue, respiratory rate, and ultrasound production during cold exposure in pups 10-12 days of age. All 3 physiological measures i...
متن کاملInnovative Methodology Laryngeal apnea in rat pups: effects of age and body temperature
Xia L, Leiter JC, Bartlett D, Jr. Laryngeal apnea in rat pups: effects of age and body temperature. J Appl Physiol 104: 269–274, 2008. First published October 25, 2007; doi:10.1152/japplphysiol.00721.2007.—In neonatal mammals of many species, including human infants, apnea and other reflex responses frequently arise from stimulation of laryngeal receptors by ingested or regurgitated liquids. Th...
متن کاملLaryngeal apnea in rat pups: effects of age and body temperature.
In neonatal mammals of many species, including human infants, apnea and other reflex responses frequently arise from stimulation of laryngeal receptors by ingested or regurgitated liquids. These reflexes, mediated by afferents in the superior laryngeal nerves (SLNs), are collectively known as the laryngeal chemoreflex (LCR) and are suspected to be responsible for some cases of the sudden infant...
متن کاملSex-Specific Consequences of Neonatal Stress on Cardio-Respiratory Inhibition Following Laryngeal Stimulation in Rat Pups
The presence of liquid near the larynx of immature mammals triggers prolonged apneas with significant O2 desaturations and bradycardias. When excessive, this reflex (the laryngeal chemoreflex; LCR) can be fatal. Our understanding of the origins of abnormal LCR are limited; however, perinatal stress and male sex are risk factors for cardio-respiratory failure in infants. Because exposure to stre...
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ژورنال
عنوان ژورنال: American Journal of Physiology-Lung Cellular and Molecular Physiology
سال: 2020
ISSN: 1040-0605,1522-1504
DOI: 10.1152/ajplung.00306.2019